When is it too far out from CRT to the chest to be considered for PCI for limited-stage SCLC?

Topics: Lung Cancer • Radiation Oncology • Thoracic Malignancies

When is the ideal window for delivering PCI for limited-stage SCLC?

Answer from: Radiation Oncologist at Community Practice

How about this answer that was not listed - "don't give it!" The evidence we hang our hat for PCI in SCLC is not just weak, it is also outdated. With the medical technology available they had at the time, it made logical sense that staging would miss brain metastases. ~50% of the studies in the...

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Radiation Oncologist at CarolinaEast Radiation Oncology
@Simul Parikh, thank you for your excellent and th...

Radiation Oncologist at Ohio State University James Cancer Center
In MR-screened populations, brain metastasis veloc...

Answer from: Radiation Oncologist at Academic Institution

I've often wondered this myself, and there's no clear evidence or guideline to my knowledge. One reference point is the EORTC trial of PCI in extensive stage SCLC, which mandated that PCI start 4-6 weeks after chemo. But probably the best way to think about this is, during what period are brain meta...

Answer from: Radiation Oncologist at Community Practice

No limit as long as no brain Mets.

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