When is lanreotide preferred over octreotide in GI neuroendocrine tumors?

As far as I am concerned, the drugs are equally effective, assuming the drugs get delivered correctly. The advantages of lanreotide are, as others have mentioned, a more reliable delivery method being given SC instead of IM. Also, lanreotide has faster absorption and it takes a shorter time to achie...

Currently, there is no evidence to favor one SSA over the other. Both randomized trials (PROMID and CLARINET) showed improved PFS with octreotide and lanreotide. However, both trials had differences in patient population, functionality, and liver tumor burden, we can't select one SSA over the other ...

Obesity can be an issue for IM injections with Sandostatin. Tough to reach the muscle and a good reason to switch to a sub-q formulation.

Patient preference. I had a patient who developed an abscess after Sandostatin, which is a deep IM injection.