When is SBRT or hypofractionated radiation appropriate as adjuvant treatment for pancreatic cancer?
What are the targets (tumor bed, positive margin, nodes etc.)?
Answer from: Radiation Oncologist at Academic Institution
There may be a variety of opinions about this question. 33Gy in 5 looks to be as least as as good as 50.4Gy in 28 in unresectable pancreatic cancer and has had some improved pathologic responses in borderline resectable pancreatic cancer in experienced hands (Hermann, JHU). However, the best data fr...
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Medical Oncologist at Siri Onclogy and hematology Infusion Service please, could we have the reference to 5-year dise...
Answer from: Radiation Oncologist at Community Practice
As @Christopher H. Crane outlines above, the management of resected pancreatic cancer is controversial and a “standard” adjuvant treatment approach has yet to be determined. We patiently await the results of RTOG 0848, the current cooperative group trial evaluating the role of conve...
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Radiation Oncologist at Washington University School of Medicine To make sure I understand the target volumes corre...
Medical Oncologist at Siri Onclogy and hematology Infusion Service most would accept that FOLFIRINOX or modified FOLF...
Answer from: Radiation Oncologist at Community Practice
In response to your questions:
1) Yes, the afferent limb is treated as an avoidance structure (organ at risk-OAR). We contour all anastomoses (HJ, PJ, and GJ), jejunum, small bowel (excluding the jejunum), and stomach as OARs.
-The&...
Answer from: Radiation Oncologist at Community Practice
Hypo will result in damage to surrounding tissues/organs if the patient lives >1 year, If expected survival is 1 year or less (as is typical for Pancreatic ca), then hypofractionated RT is fine
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Radiation Oncologist at Memorial Sloan-Kettering Cancer Center Based on what data?
please, could we have the reference to 5-year dise...