Topics:
Breast Cancer • Radiation Oncology
When offering palliative radiation for breast cancer, what dose/fractionation do you prefer and in what subset of patients do you believe derive the most benefit?
Answer from: Radiation Oncologist at Community Practice
This is the only prospective study in this setting showing short course can achieve significant palliative and well-tolerated Chatterjee et al., PMID 36868522
Answer from: Radiation Oncologist at Community Practice
GRID radiation is how I treated my most recent case of neglected/ulcerated breast tumor, and I'm really pleased with the result. We used a single oblique beam of 10X energy to deliver 15 Gy x1 of GRID using MLC shaping, with a pattern of 1 cm open per 3 cm closed. It was an almost identica...
Answer from: Radiation Oncologist at Community Practice
There is randomized data supporting no difference in survival or QOL with locoregional palliation across the board in breast cancer, so I do not offer it to all patients. I select patients using the same principles for general palliation - pain, bleeding, functional limitations, etc. I generally do ...
Answer from: Radiation Oncologist at Academic Institution
It depends on what you are trying to palliate. If the patient is having significant bleeding and the goal is to control the bleeding in a patient that is potentially curable, I use 8 Gy in a single fraction using electrons and just treat the superficial aspect of the tumor. This can be repeated if n...
Would you ever dose escalate to 30 Gy/5 fraction d...
I have used 30/5 with gross disease. If significan...
@Chirag S. Shah do you have any constraints for sk...
We do see hyperpigmentation and desquamation. We d...