When should lumbar puncture be prioritized for patients with suspected Guillain-Barre Syndrome?

I am not sure that the word "prioritized" is the critical point. A history and physical examination is the first priority, followed by an NCV and EMG. An LP is part of this work-up, but remember that if the onset is rapid and symptoms are < 5 - 7 days, the protein may be normal in GBS. The LP is imp...

There are two major reasons to do an LP in suspected GBS. One is to see if there is albuminocytologic dissociation supporting the diagnosis of GBS. LP done early in the course may be normal, so CSF does not drive early treatment decisions. It should also be noted that the IGOS study showed that a sm...