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When treating APBI with the Florence regimen, are you using daily or every other day fractionation?

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When treating APBI using the Florence regimen, do you treat QD or QOD?

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3 Answers
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Radiation Oncology · Michigan Healthcare Professionals, PC
Answered on

qD

When I started doing this at the beginning of the pandemic, I reached out to the authors of Livi study and they said that despite the study, they were treating every day without issue. Then, they wrote up their series of patients treated qD. It was effective and safe.

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Radiation Oncology · Allegheny Health Network, Pittsburgh
Answered on

We treat daily. We have compared daily to QOD and shown no difference.

Moncaliano et al., IJROBP 22022

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Radiation Oncology · New York University School of Medicine
Answered on

At NYU, we give 600cGy x 5 daily (usually prone). Our experience in more detail here:

Hardy-Abeloos et al., PMID 38183516

Shah et al., PMID 34474168

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