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When treating endometrial cancer patients with a combination of chemotherapy and vaginal cuff brachytherapy, when do you deliver cuff brachy?

Do you wait until chemotherapy completion, interdigitate between cycles 1-2 only when feasible, or between any cycle of chemotherapy? What factors would you consider in making this decision?
2 Answers
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

I prefer, most of the time, between the cycles of chemotherapy (1 to 3) based on logistics.

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Mednet Member
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Radiation Oncology · Vanderbilt-Ingram Cancer Center
Answered on

Usually by cycle 1 of chemotherapy, the patient has not had sufficient time for vaginal cuff healing. Thus, most of my brachytherapy in these interdigitated scenarios is done between cycles 2 and 3 or between cycles 3 and 4. If physician/departmental scheduling or patient intolerance of chemotherapy...

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