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When treating node positive anal squamous cell carcinoma, does your lymph node boost include only gross disease with margin or do you boost the entire nodal region?

Specifically, RTOG 0529 describes treating 50.4- 54 to the "nodal region," but other atlases (UK anal contouring) describe treating the involved node with a margin with elective nodal dose to the rest of the nodal basin.
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Radiation Oncology · Washington University School of Medicine
Answered on · Updated on

First of all, I should note that, for purposes of RTOG 0529, there are eight nodal regions: mesorectal, presacral, right and left inguinal, R+L external iliac, and R + L internal iliac. So a patient with a clinically involved right inguinal node would only receive boost treatment on the right. The c...

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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

Boost is to involved node with PTV margin and dose is a function of nodal size

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