When treating osteoporosis, does your duration of maintenance bisphosphonate therapy post anabolic therapy with PTH analogue change based on C-telopeptide levels?
How would you approach next treatment step in a patient with osteoporosis treated with Forteo x 18 months then switched to oral bisphosphonate x 3 months, and found to have low C-telopeptide levels?
1 Answer
Mednet MemberInvited Expert
Endocrinology · Stanford Health Care
Answered on · Updated on
I have treated many patients with teriparatide and conducted non-clinical studies on PTH/PTHrP receptors. Despite the fact that there are no PTH/PTHrP receptors on osteoclasts, when PTH stimulates osteoblast activity, the normal coupling via osteoprotegerin is intact, and about 4 weeks after one det...
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