When treating rectal cancer with conventional neoadjuvant chemoradiation (45 Gy to pelvis with boost to 50.4 Gy), what volume do you use for the boost?   

There is no RTOG consensus on boost volume, except to say that it should include the entire mesorectum/presacral region at involved levels + 2 cm in cc directions. According to RTOG 0822, it is recommended that the CTV extends 1 cm into bladder, vagina or prostate. Do you use this parameter for the boost volume? If so, what dose constraint do you use for bladder (as protocol states any volume of bladder > 50 Gy is unacceptable). 



Answer from: Radiation Oncologist at Academic Institution

Answer from: Radiation Oncologist at Academic Institution
Comments
Radiation Oncologist at Memorial Sloan-Kettering Cancer Center
I agree, the biggest point of emphasis is that the...
Radiation Oncologist at Washington University School of Medicine
For many cases, the proposed boost fields would pr...
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