When using conventionally fractionated breast RT, does one need to treat the whole breast to 50Gy or is 45Gy, followed by a boost satisfactory?  

Dose in many studies were often prescribed to a point rather than a volume and with 3D planning, we may be upping the breast dose.  The D2eq dose for the hypofractionated schemes are closer to 45 Gy than 50 Gy for rapidly proliferating tissues and cosmesis is better in the START trial than 50 Gy.



Answer from: Radiation Oncologist at Community Practice