When would you consider adjuvant chemoradiation in a patient with esthesioneuroblastoma?
Would gross ENE or R1 resection trigger you to consider adding chemo? If so, do you use weekly cisplatin or cisplatin/etoposide?
1 Answer
Mednet MemberInvited Expert
Medical Oncology · Johns Hopkins University School of Medicine
Answered on
In both situations, I would give cisplatin concurrently with post-operative RT. One could make an argument for the combination regimen as this is a rare tumor lacking in randomized controlled phase III trials to establish standard of care. Multimodality management is extrapolated from HNSCC and neur...
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