When would you consider obtaining tumor tissue in NF-1 associated pediatric low grade glioma?

This is definitely an evolving field. Recently, a consensus paper discussing this and other NF-related topics was published that may be helpful as below:

Packer RJ et al., Implications of new understandings of gliomas in children and adults with NF1: report of a consensus conference. Neuro Oncol. 20...