When would you consider sequential chemotherapy and radiation rather than concurrent for early stage cervical cancer with high risk pathologic features?  

The recently released STARS phase 3 RCT found improved DFS, decreased distant recurrence, with reduced toxicities for chemotherapy (cisplatin + taxol) followed by RT versus concurrent chemo-radiation.



Answer from: Radiation Oncologist at Academic Institution
Comments
Radiation Oncologist at Delaware Valley Urology Cancer Treatment Center
Can you please explain your rationale for the fina...
Radiation Oncologist at Vanderbilt-Ingram Cancer Center
Because a trial evaluated sequential CRT using Car...
at West Cancer Center and Research Institute
I really appreciate the review of the STARS trial ...
Radiation Oncologist at Vanderbilt-Ingram Cancer Center
Thanks for the comments. I meant the use of Cis/Ta...
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Answer from: Radiation Oncologist at Academic Institution