When would you omit RT for pleomorphic LCIS?

Topics: Breast Cancer • Radiation Oncology

Updated NCCN guidelines say there is no data to support radiation for pleomorphic LCIS. Previous discussion recommended radiation for LCIS https://www.themednet.org/question/1239?searchid=136699

Answer from: Radiation Oncologist at Community Practice

PLCIS in limited data appears to behave like high grade DCIS with progression to invasive disease like DCIS. It is presumed based on data that in older DCIS studies they were included as they present like DCIS with microcalcs and morphologically can be confused with DCIS (as IHC like E cad stains w...

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Radiation Oncologist at Mayo Clinic Hospital
We have a similar philosophy. Though there is a l...

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