When would you omit RT for pleomorphic LCIS?
Updated NCCN guidelines say there is no data to support radiation for pleomorphic LCIS. Previous discussion recommended radiation for LCIS https://www.themednet.org/question/1239?searchid=136699
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Mednet MemberInvited Expert
Radiation Oncology · Varian Medical Systems/Allegheny health network
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PLCIS in limited data appears to behave like high grade DCIS with progression to invasive disease like DCIS. It is presumed based on data that in older DCIS studies they were included as they present like DCIS with microcalcs and morphologically can be confused with DCIS (as IHC like E cad stains we...
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