When would you recommend standard of care over hypofractionated treatment in an elderly patient diagnosed with Glioblastoma?

Treatment of patients with newly diagnosed GBM who are >70 years of age is controversial and treatment decisions should be individualized. Some patients who are GREATER THAN 70 years of age are candidates for standard 6-week RT+TMZ and some patients who are LESS THAN 70 years of age may require modi...