When would you suspect an allergy to the dialysis membrane in patients who complain of pruritis during dialysis?  

The short answer is no. Pruritus is so common with renal disease, and allergic reactions to dialyzers are uncommon. If the pruritus can confidently be documented to be only during dialysis and not at any other time, then it may be worth trying a different dialyzer but it would take a lot for me to b...

I have had multiple discussions with my nephrology colleagues over the years who almost uniformly agree that dialysis-related pruritus is not allergic in origin. It is important to establish 2 things in this context (as noted by Dr. @Sam). Is the pruritus limited to dialysis or immediate post-dia...