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Which antidiabetic agents would you recommend to treat hyperglycemia secondary to PI3K and AKT inhibitor therapy?

2 Answers
Mednet Member
Mednet MemberInvited Expert
Endocrinology · University of Texas Southwestern Medical School
Answered on

SGLT-2 inhibitors and metformin are the preferred agents of choice for hyperglycemia with PI3K and AKT inhibitor therapy.

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Mednet Member
Mednet MemberInvited Expert
Endocrinology · Temple University Hospital
Answered on

In the patients I have seen with this condition, typically insulin is what works best.

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