Which of the many possible adjuvant chemotherapy regimens do you prefer for a fully resected extraskeletal osteosarcoma?

Important to remember that EOS mimics STS more so than skeletal OS, so the STS rules apply. It is not nearly as sensitive to SOC drugs as a skeletal OS, and CDDP and MTX have very limited activity. All this said, in a very high-risk situation of systemic Rx is planned, the drugs of choice are doxoru...