Which patients would benefit from referral to a center with pancreatic function tests such as a secretin stimulation test?

The short answer is none.

Secretin-stimulated pancreatic function tests are often used to diagnose "early" chronic pancreatitis and exocrine pancreatic insufficiency.

The problem is that the test has poor accuracy for either condition.

This is a test of pancreatic ductal cell function only, which is influenced by many factors other than chronic pancreatitis, including age, use of acid-suppressive medications, smoking, alcohol use, use of exogenous estrogen, CFTR variant(s), etc.

It also has poor...