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In which patients with hospital-acquired gram-negative bacteremia would you consider use of empiric cefiderocol before susceptibility results are available?

Paterson et al., PMID 41067237
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In which patients with hospital-acquired gram-negative bacteremia would you consider use of empiric cefiderocol before susceptibility results are available?

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1 Answer
Mednet MemberInvited Expert
Infectious Disease · UT Southwestern School of Medicine
Answered on

Unless there is a history of resistance or the antibiogram of the institution where the patient acquires the infection shows that there is a high level of resistance necessitating cefiderocol use, I would almost never use it empirically. If there is a concern for MDRO gram-negative, I usually give c...

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