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Which patients with localized esophageal adenocarcinoma, if any, would you offer nivolumab after lack of pCR to neoadjuvant FLOT?

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Would you offer adjuvant nivolumab in patients with localized esophageal adenocarcinoma after lack of pCR to neoadjuvant FLOT?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · Henry Ford Cancer Institute (HFCI)
Answered on

I have not been in such a situation, yet, but I am sure will be soon! My thought will be to start off with patients with a PDL1 score of at least 5. Not sure the degree of path response can predict immune therapy sensitivity, so at this time, I would treat all except the pCR but may also consider li...

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