Which patients with rectal cancer who have not received neoadjuvant treatment do you offer adjuvant radiation to?

Topics: Radiation Oncology • Gastrointestinal Cancers • Medical Oncology • Colorectal Cancer

Is there a subset of patients you would avoid neoadjuvant CRT and operate first?

Answer from: Medical Oncologist at Academic Institution

In order to answer this question, we may need to step back and first review the indications for radiation treatment in the neoadjuvant setting.Neoadjuvant concurrent chemoradiation or short course radiation treatment is considered to be part of the standard treatment (recommended by guidelines) for ...

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Medical Oncologist at Northwest Georgia Oncology Centers
Thank you for your answer. I know NCC...

Medical Oncologist at Mayo Clinic
NCCN guidelines recommend offering adjuvant radiat...

Answer from: Radiation Oncologist at Academic Institution

In patients with cT2N0 disease who’ve had a LAR/APR (upfront or post transanal excision for T2) and subsequently upstaged with T3 or greater, N+, or pathologic features consistent with non-optimal surgery (e.g., close radial margin, close proximal/distal margin, or low total LN recovery), the ...

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Medical Oncologist at Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center
I've never understood the rationale for the "sandw...

Answer from: Radiation Oncologist at Community Practice

The above points are thorough and well referenced. I'll focus on making a case for consideration of adjuvant XRT in some pT2-3N0 R0 or (gasp) even pT1N0 R0 settings: - pT3N0 - easiest case to be made, as these patients have been traditionally included in practice-defining trials (e.g., CAO/ARO/...

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