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Which regimen would you recommend for a young patient with node-positive, triple-negative breast cancer with significant anthracycline-induced cardiomyopathy?

Question inspired by the case of a young woman with LVEF 20-25%, asymptomatic.
1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · Ohio State University
Answered on

I would consider the NeoPact regimen, consisting of 6 cycles of docetaxel, carboplatin, and pembrolizumab, which is currently being directly compared to the Keynote-522 regimen in the SCARLET trial. Given some immune-related cardiac risks of pembrolizumab, I would strongly recommend that the patient...

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