Which sclerotherapy agents do you prefer and why?

Hypertonic saline has no risk of allergic reaction/anaphylaxis, and if you dilute it a bit, it doesn't sting yet works well. We dilute a little for large vessels and cut the strength in half for small/tiny vessels. Key is to get into the vessels without extravasation and only inject enough to blanch the vessels you see and not over-inject. If you get extravasation, milk the fluid out so it doesn't stay in the tissue. Technique is key. Watch for vessels that don't blanch with injection and treat ...