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Will you offer durva-FLOT perioperatively for adenocarcinoma of the esophagus?

In the exploratory analysis, this population didn't seem to benefit. Is there sufficient evidence to recommend perioperative FLOT ± durvalumab over neoadjuvant chemoradiation followed by resection for patients with limited disease? Would you factor in PDL1/TAP/CPS?
1 Answer
Mednet Member
Mednet Member
Medical Oncology · City of Hope Comprehensive Cancer Care
Answered on

Yes, especially distal or GEJ.

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