Topics:
Radiation Oncology • Thoracic Malignancies
Will you offer single fraction SBRT for pulmonary oligometastases?
The TROG 13.01 SAFRON-II trial used a single 28 Gy fraction. When is it appropriate to use this fractionation?
Answer from: Radiation Oncologist at Academic Institution
We use single fraction radiation frequently for most peripheral lung metastasis. In addition to TROG 13.01/SAFRON-II (randomized to 48 Gy/4 fx versus 28 Gy/1 fx, with the important footnote that dose was prescribed for 99% PTV coverage rather than the typical 95%), two other randomized trials -...
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Answer from: Radiation Oncologist at Community Practice
Yes. I recommend that small lung oligo mets be treated with SBRT. This is based on the RTOG 0915 trial, though I do not yet have abundant experience with this approach.