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Will you use vadadustat in place of an ESA in treating anemia of chronic kidney disease?

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In which dialysis patient populations would you consider using vadadustat to treat anemia of chronic kidney disease, in place of traditional ESAs?

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2 Answers
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Nephrology · IU Health
Answered on

Vadadustat is approved by the FDA only for patients who have been on dialysis for at least 3 months. It is not approved for patients with CKD not on dialysis. Its efficacy and safety are comparable to that of ESAs. I would consider using vadadustat in two patient populations: those on home dialysis ...

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Mednet Member
Mednet Member
Nephrology · Saint Lukes Nephrology Associates Of Carbon County
Answered on

I would use traditional ESA due to their known safety profile and reserve agent for an unresponsive patient. With more data, will likely change.

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