With an increase in the prevalence of MASLD in the United States population, what recipient and donor characteristics do you find favorable for acceptance of a highly steatotic graft?
Answer from: at Academic Institution
There are many different clinical and biochemical features that our surgical colleagues assess when considering potential donor liver grafts, the degree of histological steatosis being one of them. Concurrent presence of fibrosis on biopsy is important to consider, as well as the degree of micro- an...
Traditionally, macrovesicular steatosis above 30% in cadaveric donors and above 20% in living donors was considered a relatively no-go. But livers of younger donors (ideally <50 years old without major comorbidities) may have a better chance for regeneration (with less than 50% steatosis) and cou...