With what agents can you replace PPIs if they cause thrombocytopenia?

The incidence of PPI-induced thrombocytopenia is very low - and really only reported in case reports. I would suggest ensuring the low platelet count is really from the PPI (in some cases may be reasonable to re-challenge the patient), and not from a more common reason. In a recent case report on Lansoprazole-induced thrombocytopenia, the patient was switched to pantoprazole and did fine. (Saad and Mitwally, PMID 30917722). Most of the case reports are for a specific PPI. If the concern is for t...