Would accelerated hypofractionated whole breast irradiation therapy be contraindicated in a patient opting for breast conservation in the setting of breast implants?

I would say it is not contraindicated. In the clinical studies comparing conventional to hypofractionation, they did not report any increase in late effects on skin or subcutaneous tissue. Rather, in START B it was less for hypofractionation possibly because of lower total dose. The most important a...