Would elevated bone mineral density/T-score be enough to make a diagnosis of osteopetrosis?
1 Answer
Mednet MemberInvited Expert
Endocrinology · Boston University School of Medicine
Answered on
You should not make the diagnosis of osteopetrosis based on a high bone density. There are several causes for high bone density including the autosomal recessive genetic disorder sclerostosis which is caused by mutations in the STOST gene which prevents the production of functional sclerostin.
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