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Would you add an SGLT2 inhibitor to augment diuresis during a hospitalization in a patient with nephrotic syndrome, an eGFR above 30 mL/min/1.73m2, and refractory hypervolemia on an intravenous loop diuretic?
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Mednet Member
Nephrology · Columbia University
- Establish true loop diuretic refractoriness (minimum frequency: BID, the max dose depends on CrCl).
- Add sequential diuretics. Metolazone or other thiazide-like diuretics, with without amiloride or spironolactone. (Latter diuretics are preferred if the patient is hypokalemic).
- Add 25% albumin if e...