Topics:
Gynecologic Cancers • Ovarian Cancer
Would you alter neoadjuvant chemotherapy regimen for a high grade small cell neuroendocrine carcinoma of the ovary if she has already received cycle 1 of carbo/taxol?
Presented with 8cm pelvic mass and had large omental cake + significant carcinomatosis on diagnostic lap. Biopsy ultimately resulted non-epithelial ovarian cancer, however patient had already received 1 cycle NACT.
Answer from: at Academic Institution
Small cell neuroendocrine tumors of the ovary are rare and of poor prognosis. There are several steps I would take in a situation like the one described in the vignette.
Discuss poor prognosis with the patient.
Rule out occult primary that is not ovarian.
Get early involvement of medical ...
Sign in or Register to read more