Would you alter neoadjuvant chemotherapy regimen for a high grade small cell neuroendocrine carcinoma of the ovary if she has already received cycle 1 of carbo/taxol?
Presented with 8cm pelvic mass and had large omental cake + significant carcinomatosis on diagnostic lap. Biopsy ultimately resulted non-epithelial ovarian cancer, however patient had already received 1 cycle NACT.
1 Answer
Mednet Member
Gynecologic Oncology · Columbia University Medical Center
Answered on
Small cell neuroendocrine tumors of the ovary are rare and of poor prognosis. There are several steps I would take in a situation like the one described in the vignette.
- Discuss poor prognosis with the patient.
- Rule out occult primary that is not ovarian.
- Get early involvement of medical oncologis...
Join for free or sign in to see the full answer