Would you alter radiation recommendations for a patient with locally advanced rectal cancer and a history of abdominopelvic lymphoma radiation 40 years ago?

In the case of more recent RT, I would get the records in order to inform treatment recommendations. However, records are typically impossible to get in this situation. We have several options here. The first is the avoidance of radiation, as was recently reported in the PROSPECT study. (Schrag et a...

In general, if the patient did not have the prior therapy, one would recommend adjuvant radiation, and if it would benefit someone else, it would benefit this patient as well, so I would want to give adjuvant radiation if possible. The question then is whether or not the risk of added toxicity outwe...