Would you avoid a 24 hour urine collection for creatinine clearance measurement in a patient who is on fluid restriction?
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Would you avoid a 24-hour urine collection for creatinine clearance measurement in a patient who is on fluid restriction?
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2 Answers
Mednet MemberInvited Expert
Nephrology · Penn Medicine Cherry Hill
Answered on
I don't think there is a reason to avoid a 24-hour urine collection in this setting. The excretion of creatinine in a 24-hour period is independent of urine flow rate.
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Mednet MemberInvited Expert
Nephrology · University Of California San Francisco Medical Center At Parnassus
Answered on
No. The creatinine clearance should still be accurate if done correctly. The only problem may be if the urine output is lower, minor mistakes in urine collection will lead to bigger inaccuracies.
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