Would you avoid SGLT2 inhibitors in patients with urinary incontinence requiring incontinence briefs due to concern with genitourinary hygiene and risk for infections?

According to one our smart fellows "SGLT2i turns the urine into a sugary orange juice", so it should not be given at the time of UTI or in persons with high likelihood of UTI or prior recurrent UTIs. Additionally, under the real world scenario when eGFR<25 ml/min, dialysis initiation can likely be d...

I would probably avoid SGLT-2 inhibitors in this setting unless some compelling reason to use one. Other agents for renal protection should be optimized.

There’s no point in giving SGLT-2 inhibitors to those who are prone to develop urogenital infections!

I would imagine the risk is low, so I would not avoid SGLT2 in this setting. I would stop them though if someone in that situation has an infection.