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Topics:
Breast Cancer
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Medical Oncology
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NCI-CCC Tumor Board Question
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UCLA
Would you chose tamoxifen over AI for HR+ BC patients with criteria for statin therapy (e.g. LDL >190) but who are unwilling to take or didn't tolerate statin therapy?
Related Questions
Would you offer capecitabine re-challenge for a patient with metastatic breast cancer and a history of coronary vasospasm?
Is there evidence for development of more severe autoimmune toxicities for young patients vs older patients on immune checkpoint inhibitors?
Are there any scenarios you would use CDK 4/6i to treat HR-positive HER2-positive breast cancer in combination with anti-HER2 agents?
What estimated absolute benefit level of adjuvant chemotherapy for HR-pos HER2-negative breast cancer is worth recommending chemotherapy to patients?
In which situations are you comfortable with alternative dosing of ovarian suppression (e.g Lupron q3m) for premenopausal patients during adjuvant breast cancer treatment?
Do you consider post-NAC isolated tumor cells in LNs to be residual disease in TNBC to justify capecitabine?
What is your preferred adjuvant chemotherapy regimen for a patient with local recurrence of TNBC two years after completing neoadjuvant ddAC-T who declined prior adjuvant capecitabine?
Would you recommend axillary lymph node dissection in a pre-menopausal woman with ER+ PR+ HER2- IDC, s/p lumpectomy and SLN with pT1c pN1 cM0 disease, where 2 sentinel nodes are positive for macrometastasis and 1 SN is positive for micrometastasis?
In which scenarios do you stage breast cancer using CT and nuclear bone scans versus PET-CT?
How do you manage adjuvant endocrine therapy for microinvasive HR-positive disease measuring >=1mm in extension?