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Would you consider combination mycophenolate and JAKi in a patient with RA-ILD?

Is there any evidence for the safety of MMF and a JAKi in RA-ILD?
1 Answer
Mednet Member
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Rheumatology · University of Washington
Answered on

I have minimal experience combining a JAKi with mycophenolate. A patient with RA-ILD whose joints were well controlled with tofacitinib but whose ILD was progressing had MMF added to their regimen by their ILD pulmonologist. Unfortunately, after 4 months, the patient developed significant leukopenia...

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