Would you consider combining voclosporin and obinutuzumab for pure Class V lupus nephritis?

I would just swtch to obinutuzumab.

I agree with @Andras Perl . Changing his regimen is indicated since target proteinuria (<700 mg/day by 1 year) has not been achieved, and renal biopsy shows ongoing active inflammatory class V (very smart to get that bx, btw!).

Obinituzumab (OBI) is the better choice than belimumab in patients with ...