Would you consider offering neoadjuvant concurrent chemoradiation to a young (<50) patient with adenocarcinoma of the GE junction with a site of solitary metastasis (bone)?
Provided the patient can have the solitary met treated definitively with SBRT and is otherwise a good surgical candidate
Answer from: Medical Oncologist at Community Practice
In general, my approach to the patient with a solitary site of metastasis from GE junction cancer is to start with chemotherapy. If their disease is responsive over a few scans, it’s reasonable to then “consolidate” with chemoradiotherapy to the primary tumor site.
If progre...
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