Would you consider perioperative antifibrinolytics for mild factor 7 deficiency undergoing surgery?
Factor 7 levels were previously mildly low at 20-40%, but are now normalized to >60%. No prior surgeries for comparison, but has a history of heavy menses.
Would you only use antifibrinolytics if factor 7 was low, or would you also consider its use with the history of low factor 7 levels despite current normal levels?
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At what factor 7 level would you typically add replacement factor for perioperative care?
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1 Answer
Mednet MemberInvited Expert
Hematology · University of Pittsburgh Medical Center
Answered on
I do use antifibrinolytics in factor VII deficiency; however, it depends on the specifics of the surgery (i.e., mucosal surface surgery, sequelae of bleeding should it occur - spine vs oral), the patient's bleeding history, and the factor VII level.
Here, I wonder if the original diagnosis was corre...
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