Would you consider perioperative immunotherapy for a patient with locally advanced, resectable gastric cancer but not a candidate for chemotherapy?

Topics: Gastrointestinal Cancers • Medical Oncology • Gastroesophageal Cancer

On occasion, patients with locally advanced gastric cancer are poor candidates for FLOT-like chemotherapy. Should such patients be taken to surgery upfront or following a course of RT? Would a short course of perioperative immunotherapy be considered in this situation?

Answer from: Medical Oncologist at Academic Institution

Some aspects of the management in this situation are influenced by the surgical candidacy. If this patient is not a candidate for chemotherapy it would be critical to have a multidisciplinary assessment for surgical candidacy. Unfit for chemo but fit for surgery is a relatively uncommon ...

Comments

Medical Oncologist at Walter Reed Natl Military Medcl Center
Thanks for your response! My patient is fairly uni...

Medical Oncologist at Walter Reed Natl Military Medcl Center
PDL1 CPS > 90

Medical Oncologist at Massachusetts General Hospital
I think in the absence of data (there is some data...

Related Questions