Would you consider PMRT for non-mass like enhancement >5cm on breast MRI that resolves with NAC and has a pCR?
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Do you consider the size of non-mass enhacement when you clinically stage breast cancer patients?
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2 Answers
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on
For clinical T3No with pCR, limited data suggest low risk of LRR and I usually avoid PMRT unless triple negative or multiple adverse factors on pretreatment pathology and imaging.
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Radiation Oncology · Arthur JE Child Comprehensive Cancer Centre, Calgary
Answered on
If the non-mass like enhancement is considered in your clinical staging as cT3, we can look to the old NSABP experience on rates and patterns of LRR in patients treated with NAC but without PMRT, i.e., NSABP B-18 and B-27. They examined the 10-year cumulative incidence of LRR in patients with >5cm t...
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