Would you consider post-mastectomy radiation in patient with a triple negative tumor pT2N0?
What high risk pathology factors would you consider in making your decision one way or another?Would it matter if this patient was elderly vs young? Would it matter if this was a recurrent primary and had received prior whole breast radiation or APBI?
2 Answers
Mednet Member
Radiation Oncology · Cancer Care Centers of Brevard
Answered on · Updated on
In borderline cases, I look at some of the retrospective data showing higher recurrence rates in patients with close margins, premenopausal status, higher grade and T2 tumors.
In the specific case in the OP, I would discuss the data from the Chinese randomized trial (green journal 2011) showing an OS...
Join for free or sign in to see the full answer
Mednet MemberInvited Expert
Radiation Oncology · Allegheny Health Network, Pittsburgh
Answered on
In a case of a de novo T2N0, 5 cm triple negative breast cancer, I would discuss the data available and explain that it could be considered but my recommendation would be no PMRT. However, I would explain that her risk of locoregional recurrence is likely higher than that seen with a T1-2N0 ER+ canc...
Join for free or sign in to see the full answer