Would you consider radiation to the axillary lymph nodes ONLY (omitting chest wall) for patients with 1-3 axillary LNs who would otherwise not receive post-mastectomy radiation (T1-2, clear margins etc) when these patients have or will undergo breast reconstruction?

I am not a fan of this approach. In patients with node positive disease without a locally advanced primary, the majority of local-regional relapses are actually still on the chest wall. Perhaps there is rationale, but if I am to treat regional nodes, I would include the chest wall. I have occasional...

In AMAROS study, they allowed RNI without chest wall RT in the RT arm. In practice, if we feel the patient doesn't need PMRT ( meaning chest wall), then favor dissection over RNI. That being said, it is a reasonable alternative if the patient understands the risks and benefits of either approach (RN...

Agree with @Dr. First Last. Though allowed in AMAROS, I do not recommend treatment to axilla only, but will always include the chest wall if there is no previous RT.

It is important in my opinion to focus on oncologic outcomes first (covering chest wall due to risk of locoregional relapse).