Would you consider reserving enfortumab + pembrolizumab combination as second line after progression post platinum-based chemotherapy?

In urothelial cancer, as in most metastatic solid tumors, your optimal outcome comes from up front therapy, "saving things for later" is not usually the best management approach. As noted by the good Dr. @Dr. First Last, given the info we have regarding EV 302 (press release), this regimen may becom...

The standard of care for the treatment of metastatic urothelial cancer for several decades has been first line therapy with a cisplatin based combination regimen. For patients not eligible to receive cisplatin, a carboplatin doublet has often been recommended although in multiple studies, overall su...