Would you consider retrying a platinum based chemotherapy agent in a platinum resistant ovarian cancer patient?

Yes, I would consider the use of platinum agent again, especially if it has been a long time since their last platinum therapy. I could consider the use of Cisplatin in this case or Carboplatin.

The GCOG consensus statement recommends the following timelines for platinum response classifications:

(1) ...

Yes, definitely.

There are several case series showing a good response rate of weekly carbo (AUC2) and paclitaxel (60mg/m2) (one of several refs here). Anecdotally, we have excellent responses with minimal risk of toxicity using this regimen. There is also data from MSKCC that patients with platinum ...

Yes, I would consider retrying a platinum in combination with another agent.

In particular, I have had good anecdotal success with cis/cytoxan in this population (especially with BRCA deleterious mutation).