Would you consider salvage SRS in a young patient with locally recurrent ATRT?

If so, what dose would you consider in the setting of complete and incomplete repeat surgical resection? How would you sequence this with salvage systemic therapy?

1 Answer

Mednet Member

Radiation Oncology · Harvard Medical School

Answered on

Radiotherapy plays an important role in the curative management of ATRT.

[Chi et al, JCO 2009; Reddy et al JCO 2020].

When relapse occurs, even if it is local, the overall prognosis is often poor. However, I am assuming that this was previously treated, and I would consider re-irradiation with SRS as ...

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