Would you consider starting short-term metformin in an otherwise healthy patient who is beginning high-dose glucocorticoids to prevent glucocorticoid-induced insulin resistance?

Would you start metformin to prevent hyperglycemia in a healthy individual requiring high-dose steroids?

• Yes, but only in patients with obesity
• Yes, but only if steroid therapy is anticipated to be greater than 3 months
• No, I would not start metformin in patients without prediabetes or risk factors for insulin resistance
• Other